Diabetes is regarded one of the most challenging global health issues of the 21st century. Especially the Global South is facing a situation in which it has to tackle a so-called double burden of diseases, struggling with infectious diseases and non-communicable diseases simultaneously. Taking the situation of diabetes diagnostics in Uganda as point of departure, Arlena’s research aims to display how the introduction and translation of global health technologies contributes to the development of novel infrastructural engagements in the case of chronic diseases. On a local level the incorporation of new therapeutic proficiencies comes with new obligations. Here the use of diagnostic technologies enacts and requires new motilities of patients and health care personnel alike. This involves tracking how users of new therapeutic interventions manage, change and build their own infrastructural responses, employ creativity and shift their life worlds in order to straighten out uncertainty in service provision. Her PhD-research attempts to contribute to ongoing anthropological discourses within science and technology, as they are essential parts of the political and social worlds we inhabit as well as engagements with everyday dimensions of knowledge production.